Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase-1 (Homo sapiens (Human)) | BDBM50538547![]() (CHEMBL4648504) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co., Inc. Curated by ChEMBL | Assay Description Inhibition of human arginase1 in presence of DNTB by thio ornithine generation assay | ACS Med Chem Lett 11: 582-588 (2020) Article DOI: 10.1021/acsmedchemlett.0c00058 BindingDB Entry DOI: 10.7270/Q26113VN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens (Human)) | BDBM50538547![]() (CHEMBL4648504) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Arg1 | Citation and Details Article DOI: 10.1016/j.bmc.2020.115658 BindingDB Entry DOI: 10.7270/Q2WS8XZC | |||||||||||
More data for this Ligand-Target Pair |