Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase-1 (Homo sapiens (Human)) | BDBM50561036 (CHEMBL4778978) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate a... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00195 BindingDB Entry DOI: 10.7270/Q2542SD6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens (Human)) | BDBM50561036 (CHEMBL4778978) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Arg1 by TOGA assay | Citation and Details Article DOI: 10.1016/j.bmc.2020.115658 BindingDB Entry DOI: 10.7270/Q2WS8XZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens (Human)) | BDBM50561036 (CHEMBL4778978) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ARG1 in HEK293 cells by cell based assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00195 BindingDB Entry DOI: 10.7270/Q2542SD6 | |||||||||||
More data for this Ligand-Target Pair |