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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arginase-1' and Ligand = 'BDBM50577480'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arginase-1


(Homo sapiens (Human))
BDBM50577480
PNG
(CHEMBL4862982)
Show SMILES CO[C@H]1CN[C@@H]([C@@H]1CCCB(O)O)C(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 46n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate a...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.1c00195
BindingDB Entry DOI: 10.7270/Q2542SD6
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM50577480
PNG
(CHEMBL4862982)
Show SMILES CO[C@H]1CN[C@@H]([C@@H]1CCCB(O)O)C(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.80E+4n/an/an/an/a


TBA

Assay Description
Inhibition of human ARG1 in HEK293 cells by cell based assay


Citation and Details

Article DOI: 10.1021/acsmedchemlett.1c00195
BindingDB Entry DOI: 10.7270/Q2542SD6
More data for this
Ligand-Target Pair