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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Arginase-2, mitochondrial' and Ligand = 'BDBM50427912'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50427912
PNG
(CHEMBL2326094)
Show SMILES N[C@](CCCCB(O)O)(CCN1CCc2ccccc2C1)C(O)=O |r|
Show InChI InChI=1S/C17H27BN2O4/c19-17(16(21)22,8-3-4-10-18(23)24)9-12-20-11-7-14-5-1-2-6-15(14)13-20/h1-2,5-6,23-24H,3-4,7-13,19H2,(H,21,22)/t17-/m1/s1
PDB
MMDB

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Article
PubMed
n/an/a 1.09E+3n/an/an/an/an/an/a



Institutes for Pharmaceutical Discovery , LLC

Curated by ChEMBL


Assay Description
Inhibition of human recombinant fully active truncated form of arginase 2 overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea ...


J Med Chem 56: 2568-80 (2013)


Article DOI: 10.1021/jm400014c
BindingDB Entry DOI: 10.7270/Q2BC40WP
More data for this
Ligand-Target Pair