BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Aromatase' and Ligand = 'BDBM50035204'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50035204 (4-(6-Methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...) Show SMILES COc1ccc2CCC3C(C3c2c1)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
American University of Ras Al Khaimah Curated by ChEMBL					Assay Description Inhibition of human placental aromatase				Eur J Med Chem 102: 375-86 (2015) Article DOI: 10.1016/j.ejmech.2015.08.010 BindingDB Entry DOI: 10.7270/Q2ZC84Q6
American University of Ras Al Khaimah Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50035204 (4-(6-Methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...) Show SMILES COc1ccc2CCC3C(C3c2c1)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
American University of Ras Al Khaimah Curated by ChEMBL					Assay Description Inhibition of human placental aromatase				Eur J Med Chem 102: 375-86 (2015) Article DOI: 10.1016/j.ejmech.2015.08.010 BindingDB Entry DOI: 10.7270/Q2ZC84Q6
American University of Ras Al Khaimah Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50035204 (4-(6-Methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...) Show SMILES COc1ccc2CCC3C(C3c2c1)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of human placental microsome CYP19				Bioorg Med Chem Lett 20: 3050-64 (2010) Article DOI: 10.1016/j.bmcl.2010.03.113 BindingDB Entry DOI: 10.7270/Q2CJ8FFS
Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50035204 (4-(6-Methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...) Show SMILES COc1ccc2CCC3C(C3c2c1)c1ccncc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description In vitro inhibition of rat ovarian microsomal Cytochrome P450 19A1				J Med Chem 38: 2103-11 (1995) BindingDB Entry DOI: 10.7270/Q2NV9H9S
Universität des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50035204 (4-(6-Methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...) Show SMILES COc1ccc2CCC3C(C3c2c1)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Inhibition of Human placental Cytochrome P450 19A1				J Med Chem 38: 2103-11 (1995) BindingDB Entry DOI: 10.7270/Q2NV9H9S
Universität des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50035204 (4-(6-Methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...) Show SMILES COc1ccc2CCC3C(C3c2c1)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Inhibition of Human placental Cytochrome P450 19A1				J Med Chem 38: 2103-11 (1995) BindingDB Entry DOI: 10.7270/Q2NV9H9S
Universität des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair