Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Aromatase' and Ligand = 'BDBM50097373'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50097373 (4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...) Show SMILES O=c1c2ccccc2oc2c(Cn3ccnc3)ccc(C#N)c12 Show InChI InChI=1S/C18H11N3O2/c19-9-12-5-6-13(10-21-8-7-20-11-21)18-16(12)17(22)14-3-1-2-4-15(14)23-18/h1-8,11H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of human placental microsome cytochrome P450 19A1 aromatase				J Med Chem 44: 672-80 (2001) BindingDB Entry DOI: 10.7270/Q28S4P6H
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50097373 (4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...) Show SMILES O=c1c2ccccc2oc2c(Cn3ccnc3)ccc(C#N)c12 Show InChI InChI=1S/C18H11N3O2/c19-9-12-5-6-13(10-21-8-7-20-11-21)18-16(12)17(22)14-3-1-2-4-15(14)23-18/h1-8,11H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (BHU) Curated by ChEMBL					Assay Description Inhibition of human aromatase using [1beta,2beta3H]-]testosterone as substrate				Eur J Med Chem 177: 116-143 (2019) Article DOI: 10.1016/j.ejmech.2019.05.023 BindingDB Entry DOI: 10.7270/Q2W099B9
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50097373 (4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...) Show SMILES O=c1c2ccccc2oc2c(Cn3ccnc3)ccc(C#N)c12 Show InChI InChI=1S/C18H11N3O2/c19-9-12-5-6-13(10-21-8-7-20-11-21)18-16(12)17(22)14-3-1-2-4-15(14)23-18/h1-8,11H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPH				J Med Chem 52: 143-50 (2009) Article DOI: 10.1021/jm800945c BindingDB Entry DOI: 10.7270/Q2SQ9080
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50097373 (4-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-1-c...) Show SMILES O=c1c2ccccc2oc2c(Cn3ccnc3)ccc(C#N)c12 Show InChI InChI=1S/C18H11N3O2/c19-9-12-5-6-13(10-21-8-7-20-11-21)18-16(12)17(22)14-3-1-2-4-15(14)23-18/h1-8,11H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
American University of Ras Al Khaimah Curated by ChEMBL					Assay Description Inhibition of human placental aromatase in presence of [1beta,2beta-3H] testosterone by Thompson and Siiteri method				Eur J Med Chem 102: 375-86 (2015) Article DOI: 10.1016/j.ejmech.2015.08.010 BindingDB Entry DOI: 10.7270/Q2ZC84Q6
					More data for this Ligand-Target Pair