Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aromatase (Homo sapiens (Human)) | BDBM85573![]() (7-Hydroxy-flavone, 5h) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | 37 |
Cardiff University | Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes. | J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS | |||||||||||
More data for this Ligand-Target Pair |