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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aspartate aminotransferase, cytoplasmic' and Ligand = 'BDBM50462523'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aspartate aminotransferase, cytoplasmic


(Homo sapiens)		BDBM50462523
PNG
(CHEMBL4241742)
Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)cc1
Show InChI InChI=1S/C20H22N4O2/c1-26-16-7-5-15(6-8-16)22-20(25)24-13-11-23(12-14-24)19-4-2-3-18-17(19)9-10-21-18/h2-10,21H,11-14H2,1H3,(H,22,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



California Institute for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay

Bioorg Med Chem Lett 28: 2675-2678 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.061
BindingDB Entry DOI: 10.7270/Q2MC92P6
More data for this
Ligand-Target Pair