Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ataxin-1' and Ligand = 'BDBM50233155'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ataxin-1 (Homo sapiens (Human))	BDBM50233155 (CHEMBL4080953 | US11124490, Compound 28b) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=O)Nc2cc(Cl)c(F)c(Cl)c2)c(Cl)cc1Cl Show InChI InChI=1S/C18H16Cl4FN3O3S/c1-25-2-4-26(5-3-25)30(28,29)16-8-11(12(19)9-13(16)20)18(27)24-10-6-14(21)17(23)15(22)7-10/h6-9H,2-5H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	55.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...				Citation and Details BindingDB Entry DOI: 10.7270/Q29Z982P
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