Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ataxin-1' and Ligand = 'BDBM50233160'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ataxin-1 (Homo sapiens (Human))	BDBM50233160 (CHEMBL4071490 | US11124490, Compound 3h) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1C#N Show InChI InChI=1S/C18H13Cl2F2N3O4S/c19-13-8-14(20)17(30(27,28)25-1-3-29-4-2-25)7-11(13)18(26)24-10-5-15(21)12(9-23)16(22)6-10/h5-8H,1-4H2,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...				Citation and Details BindingDB Entry DOI: 10.7270/Q29Z982P
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