Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ataxin-1' and Ligand = 'BDBM50233186'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ataxin-1 (Homo sapiens (Human))	BDBM50233186 (CHEMBL4070002 | US11124490, Compound 23) Show SMILES Fc1cc(NS(=O)(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C16H13Cl2F3N2O5S2/c17-10-7-11(18)15(30(26,27)23-1-3-28-4-2-23)8-14(10)29(24,25)22-9-5-12(19)16(21)13(20)6-9/h5-8,22H,1-4H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...				Citation and Details BindingDB Entry DOI: 10.7270/Q29Z982P
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