Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'B-cell lymphoma 6 protein' and Ligand = 'BDBM522280'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B-cell lymphoma 6 protein (Homo sapiens)	BDBM522280 (US11161839, Example 10a) Show SMILES Cn1c2ccc(Nc3ccnc(Cl)c3C#N)cc2c(NC(C)(C)c2ncc(cn2)C2CC2)cc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BCOR peptide binding to human BCL6 expressed in Escherichia coli measured after 270 mins by BCOR ULight TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00946 BindingDB Entry DOI: 10.7270/Q2R21585
					More data for this Ligand-Target Pair				3D Structure (crystal)
B-cell lymphoma 6 protein (Homo sapiens)	BDBM522280 (US11161839, Example 10a) Show SMILES Cn1c2ccc(Nc3ccnc(Cl)c3C#N)cc2c(NC(C)(C)c2ncc(cn2)C2CC2)cc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human BCL6 (5 to 129 residues) expressed in Escherichia coli BL21-AI using BCOR-AF633 peptide as substrate measured after 2 hrs by TR-F...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00946 BindingDB Entry DOI: 10.7270/Q2R21585
					More data for this Ligand-Target Pair				3D Structure (crystal)
B-cell lymphoma 6 protein (Homo sapiens)	BDBM522280 (US11161839, Example 10a) Show SMILES Cn1c2ccc(Nc3ccnc(Cl)c3C#N)cc2c(NC(C)(C)c2ncc(cn2)C2CC2)cc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human BCL6 (5 to 129 residues) expressed in Escherichia coli BL21-AI using BCOR-AF633 peptide as substrate measured after 2 hrs by TR-F...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00946 BindingDB Entry DOI: 10.7270/Q2R21585
					More data for this Ligand-Target Pair				3D Structure (crystal)
B-cell lymphoma 6 protein (Homo sapiens)	BDBM522280 (US11161839, Example 10a) Show SMILES Cn1c2ccc(Nc3ccnc(Cl)c3C#N)cc2c(NC(C)(C)c2ncc(cn2)C2CC2)cc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02174 BindingDB Entry DOI: 10.7270/Q2WQ07TK
					More data for this Ligand-Target Pair				3D Structure (crystal)
B-cell lymphoma 6 protein (Homo sapiens)	BDBM522280 (US11161839, Example 10a) Show SMILES Cn1c2ccc(Nc3ccnc(Cl)c3C#N)cc2c(NC(C)(C)c2ncc(cn2)C2CC2)cc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human nanoLuc-tagged BCL6 expressed in HEK293T cells coexpressing HaloTag-SMRT using NanoBRET furimazine substrate incubated for 6 hrs ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00946 BindingDB Entry DOI: 10.7270/Q2R21585
					More data for this Ligand-Target Pair				3D Structure (crystal)
B-cell lymphoma 6 protein (Homo sapiens)	BDBM522280 (US11161839, Example 10a) Show SMILES Cn1c2ccc(Nc3ccnc(Cl)c3C#N)cc2c(NC(C)(C)c2ncc(cn2)C2CC2)cc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02174 BindingDB Entry DOI: 10.7270/Q2WQ07TK
					More data for this Ligand-Target Pair				3D Structure (crystal)
B-cell lymphoma 6 protein (Homo sapiens)	BDBM522280 (US11161839, Example 10a) Show SMILES Cn1c2ccc(Nc3ccnc(Cl)c3C#N)cc2c(NC(C)(C)c2ncc(cn2)C2CC2)cc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human BCL6 BDB domain by SPR assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00946 BindingDB Entry DOI: 10.7270/Q2R21585
					More data for this Ligand-Target Pair				3D Structure (crystal)