Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'B-cell receptor CD22' and Ligand = 'BDBM50274304'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B-cell receptor CD22 (Homo sapiens (Human))	BDBM50274304 (CHEMBL504353 | p-Methoxyphenyl (9-(4'-carboxy-4-bi...) Show SMILES COc1ccc(O[C@@H]2O[C@H](CO[C@@]3(C[C@H](O)[C@@H](NC(=O)CO)[C@@H](O3)[C@H](O)[C@H](O)CNCc3ccc(cc3)-c3ccc(cc3)C(O)=O)C(O)=O)[C@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C38H46N2O17/c1-53-23-10-12-24(13-11-23)55-36-33(48)32(47)31(46)27(56-36)18-54-38(37(51)52)14-25(42)29(40-28(44)17-41)34(57-38)30(45)26(43)16-39-15-19-2-4-20(5-3-19)21-6-8-22(9-7-21)35(49)50/h2-13,25-27,29-34,36,39,41-43,45-48H,14-18H2,1H3,(H,40,44)(H,49,50)(H,51,52)/t25-,26+,27+,29+,30+,31-,32-,33+,34+,36+,38+/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gifu University Curated by ChEMBL					Assay Description Binding affinity to biotinylated human CD22-human IgG1 chimeric protein expressed in mouse J558LST6 cells by flow cytometry				J Med Chem 51: 6665-81 (2008) Article DOI: 10.1021/jm8000696 BindingDB Entry DOI: 10.7270/Q23X86GN
					More data for this Ligand-Target Pair