Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM156407'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM156407 (US9018381, 30 | US9248140, 30) Show SMILES COP(O)(=O)O[C@H](C1CCN(CC1)c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(N[C@H](CCN2CCOCC2)CSc2ccccc2)c(c1)S(=O)(=O)C(F)(F)F)c1ccccc1-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C47H51ClF3N4O10PS3/c1-63-66(57,58)65-45(42-10-6-5-9-41(42)33-11-15-36(48)16-12-33)34-21-25-55(26-22-34)38-17-13-35(14-18-38)46(56)53-69(61,62)40-19-20-43(44(31-40)68(59,60)47(49,50)51)52-37(23-24-54-27-29-64-30-28-54)32-67-39-7-3-2-4-8-39/h2-20,31,34,37,45,52H,21-30,32H2,1H3,(H,53,56)(H,57,58)/t37-,45-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...				US Patent US9018381 (2015) BindingDB Entry DOI: 10.7270/Q2BC3X8D
					More data for this Ligand-Target Pair