Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM60828![]() (ABT-199 | BDBM189459 | US10213433, Compound 5 | US...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM60828![]() (ABT-199 | BDBM189459 | US10213433, Compound 5 | US...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair |