Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-galactoside alpha-2,6-sialyltransferase 1 (Homo sapiens (Human)) | BDBM50501640 (CHEMBL4102509) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC method | J Med Chem 60: 2135-2141 (2017) Article DOI: 10.1021/acs.jmedchem.6b01644 BindingDB Entry DOI: 10.7270/Q2XP77Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactoside alpha-2,6-sialyltransferase 1 (Rattus norvegicus) | BDBM50501640 (CHEMBL4102509) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat liver ST6Gal-1 using p-nitrophenyl-DL-alanine measured up to 20 mins by HPLC analysis | Citation and Details Article DOI: 10.1016/j.bmc.2020.115561 BindingDB Entry DOI: 10.7270/Q25M69DR | |||||||||||
More data for this Ligand-Target Pair |