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Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-glucuronidase' and Ligand = 'BDBM50540963'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-glucuronidase


(Escherichia coli (Enterobacteria))
BDBM50540963
PNG
(CHEBI:6146 | Kumanon G)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(oc2c(-[#6@H]-3-[#6]=[#6](-[#6])-[#6]-[#6@H](-[#6@@H]-3-[#6](=O)-c3ccc(-[#8])cc3-[#8])-c3ccc(-[#8])cc3-[#8])c(-[#8])cc(-[#8])c2c1=O)-c1ccc(-[#8])cc1-[#8] |r,t:11|
Show InChI InChI=1S/C40H36O11/c1-18(2)4-8-26-38(50)36-33(48)17-32(47)35(40(36)51-39(26)25-11-7-22(43)16-31(25)46)28-13-19(3)12-27(23-9-5-20(41)14-29(23)44)34(28)37(49)24-10-6-21(42)15-30(24)45/h4-7,9-11,13-17,27-28,34,41-48H,8,12H2,1-3H3/t27-,28-,34-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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MCE
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



University of KwaZulu-Natal

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli beta-glucuronidase


Eur J Med Chem 187: (2020)


Article DOI: 10.1016/j.ejmech.2019.111921
BindingDB Entry DOI: 10.7270/Q29W0K1V
More data for this
Ligand-Target Pair
Beta-glucuronidase


(Homo sapiens (Human))
BDBM50540963
PNG
(CHEBI:6146 | Kumanon G)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(oc2c(-[#6@H]-3-[#6]=[#6](-[#6])-[#6]-[#6@H](-[#6@@H]-3-[#6](=O)-c3ccc(-[#8])cc3-[#8])-c3ccc(-[#8])cc3-[#8])c(-[#8])cc(-[#8])c2c1=O)-c1ccc(-[#8])cc1-[#8] |r,t:11|
Show InChI InChI=1S/C40H36O11/c1-18(2)4-8-26-38(50)36-33(48)17-32(47)35(40(36)51-39(26)25-11-7-22(43)16-31(25)46)28-13-19(3)12-27(23-9-5-20(41)14-29(23)44)34(28)37(49)24-10-6-21(42)15-30(24)45/h4-7,9-11,13-17,27-28,34,41-48H,8,12H2,1-3H3/t27-,28-,34-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.40E+3n/an/an/an/an/an/a



University of KwaZulu-Natal

Curated by ChEMBL


Assay Description
Inhibition of whole human gut bacterial beta-glucuronidase


Eur J Med Chem 187: (2020)


Article DOI: 10.1016/j.ejmech.2019.111921
BindingDB Entry DOI: 10.7270/Q29W0K1V
More data for this
Ligand-Target Pair