Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase TEM (Escherichia coli) | BDBM50076678 ((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against TEM-1 (class A) beta-lactamase | Bioorg Med Chem Lett 9: 991-6 (1999) BindingDB Entry DOI: 10.7270/Q2TB163Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase TEM (Escherichia coli) | BDBM50076678 ((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trio...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzyme | Bioorg Med Chem Lett 14: 1299-304 (2004) Article DOI: 10.1016/j.bmcl.2003.12.037 BindingDB Entry DOI: 10.7270/Q22Z14ZG | |||||||||||
More data for this Ligand-Target Pair |