Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM136547'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM136547 (US8865701, 19 | US9505739, 19) Show SMILES Clc1ccc2c(CCC[C@]22CNC[C@H]2C(=O)N2CCC(CC2)c2ccccc2)c1 |r| Show InChI InChI=1S/C25H29ClN2O/c26-21-8-9-22-20(15-21)7-4-12-25(22)17-27-16-23(25)24(29)28-13-10-19(11-14-28)18-5-2-1-3-6-18/h1-3,5-6,8-9,15,19,23,27H,4,7,10-14,16-17H2/t23-,25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	920	n/a	n/a	n/a	n/a	6.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...				US Patent US9505739 (2016) BindingDB Entry DOI: 10.7270/Q2C53JST
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM136547 (US8865701, 19 | US9505739, 19) Show SMILES Clc1ccc2c(CCC[C@]22CNC[C@H]2C(=O)N2CCC(CC2)c2ccccc2)c1 |r| Show InChI InChI=1S/C25H29ClN2O/c26-21-8-9-22-20(15-21)7-4-12-25(22)17-27-16-23(25)24(29)28-13-10-19(11-14-28)18-5-2-1-3-6-18/h1-3,5-6,8-9,15,19,23,27H,4,7,10-14,16-17H2/t23-,25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	920	n/a	n/a	n/a	n/a	6.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...				US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1
					More data for this Ligand-Target Pair