Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM136550'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM136550 (US8865701, 31 | US9505739, 31) Show SMILES CC(C)c1cccc2c1CCC[C@]21CNC[C@H]1C(=O)N1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C28H36N2O/c1-20(2)23-10-6-12-25-24(23)11-7-15-28(25)19-29-18-26(28)27(31)30-16-13-22(14-17-30)21-8-4-3-5-9-21/h3-6,8-10,12,20,22,26,29H,7,11,13-19H2,1-2H3/t26-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	6.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...				US Patent US9505739 (2016) BindingDB Entry DOI: 10.7270/Q2C53JST
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM136550 (US8865701, 31 | US9505739, 31) Show SMILES CC(C)c1cccc2c1CCC[C@]21CNC[C@H]1C(=O)N1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C28H36N2O/c1-20(2)23-10-6-12-25-24(23)11-7-15-28(25)19-29-18-26(28)27(31)30-16-13-22(14-17-30)21-8-4-3-5-9-21/h3-6,8-10,12,20,22,26,29H,7,11,13-19H2,1-2H3/t26-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	6.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...				US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1
					More data for this Ligand-Target Pair