Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM136551'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM136551 (US8865701, 38 | US9505739, 38) Show SMILES O=C([C@@H]1CNC[C@]11CCSc2ccccc12)N1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C24H28N2OS/c27-23(26-13-10-19(11-14-26)18-6-2-1-3-7-18)21-16-25-17-24(21)12-15-28-22-9-5-4-8-20(22)24/h1-9,19,21,25H,10-17H2/t21-,24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	6.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...				US Patent US9505739 (2016) BindingDB Entry DOI: 10.7270/Q2C53JST
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM136551 (US8865701, 38 | US9505739, 38) Show SMILES O=C([C@@H]1CNC[C@]11CCSc2ccccc12)N1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C24H28N2OS/c27-23(26-13-10-19(11-14-26)18-6-2-1-3-7-18)21-16-25-17-24(21)12-15-28-22-9-5-4-8-20(22)24/h1-9,19,21,25H,10-17H2/t21-,24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	6.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...				US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1
					More data for this Ligand-Target Pair