Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM148186'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM148186 (US8962616, 15) Show SMILES Cc1nc(oc1C)[C@H]1CC2CSC(N)=N[C@]2(CO1)c1ccc(F)cc1F |c:14| Show InChI InChI=1S/C18H19F2N3O2S/c1-9-10(2)25-16(22-9)15-5-11-7-26-17(21)23-18(11,8-24-15)13-4-3-12(19)6-14(13)20/h3-4,6,11,15H,5,7-8H2,1-2H3,(H2,21,23)/t11?,15-,18+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...				US Patent US8962616 (2015) BindingDB Entry DOI: 10.7270/Q20Z7216
					More data for this Ligand-Target Pair