Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50569348'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50569348 (CHEMBL4856179) Show SMILES CC1(Cc2cnccc2C(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F |c:11| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BACE1 in human SH-SY5Y cells expressing APP assessed as reduction in Abeta40 by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113270 BindingDB Entry DOI: 10.7270/Q21R6V8Q
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM50569348 (CHEMBL4856179) Show SMILES CC1(Cc2cnccc2C(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F |c:11| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BACE1 (unknown origin) by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113270 BindingDB Entry DOI: 10.7270/Q21R6V8Q
					More data for this Ligand-Target Pair