Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM477881'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 2 (Homo sapiens (Human))	BDBM477881 (US10889579, Example 101) Show SMILES C[C@]1(C=CSC(N)=N1)c1cc(\C=C(/F)c2ccc(cn2)C#N)ccc1F |c:2,6| Show InChI InChI=1S/C19H14F2N4S/c1-19(6-7-26-18(23)25-19)14-8-12(2-4-15(14)20)9-16(21)17-5-3-13(10-22)11-24-17/h2-9,11H,1H3,(H2,23,25)/b16-9-/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	601	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...				US Patent US10889579 (2021) BindingDB Entry DOI: 10.7270/Q241715H
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