Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Bifunctional dihydrofolate reductase-thymidylate synthase (Toxoplasma gondii) | BDBM50074725![]() (6-tert-Butyl-5,6,7,8-tetrahydro-quinazoline-2,4-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description The ability of the compound to inhibit T. gondii Dihydrofolate reductase was tested | J Med Chem 42: 1007-17 (1999) Article DOI: 10.1021/jm980572i BindingDB Entry DOI: 10.7270/Q2513XCR | |||||||||||
More data for this Ligand-Target Pair |