Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50002861'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional epoxide hydrolase 2 (Mus musculus (Mouse))	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of phosphatase activity of full length mouse soluble epoxide hydrolase pre-incubated for 30 mins before FDP substrate addition by fluoresc...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Mus musculus (Mouse))	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of phosphatase activity of full length mouse soluble epoxide hydrolase pre-incubated for 30 mins before FDP substrate addition by fluoresc...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Rattus norvegicus)	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of phosphatase activity of full length rat soluble epoxide hydrolase pre-incubated for 30 mins before FDP substrate addition by fluorescen...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Rattus norvegicus)	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of phosphatase activity of full length rat soluble epoxide hydrolase pre-incubated for 30 mins before FDP substrate addition by fluorescen...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of phosphatase activity of full length human soluble epoxide hydrolase pre-incubated for 30 mins before FDP substrate addition by fluoresc...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of phosphatase activity of full length human soluble epoxide hydrolase pre-incubated for 30 mins before FDP substrate addition by fluoresc...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of hydrolase activity of full length human soluble epoxide hydrolase pre-incubated for 30 mins before PHOME substrate addition by fluoresc...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Rattus norvegicus)	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of hydrolase activity of full length rat soluble epoxide hydrolase pre-incubated for 30 mins before PHOME substrate addition by fluorescen...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of hydrolase activity of full length human soluble epoxide hydrolase pre-incubated for 30 mins before PHOME substrate addition by fluoresc...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Mus musculus (Mouse))	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of hydrolase activity of full length mouse soluble epoxide hydrolase pre-incubated for 30 mins before PHOME substrate addition by fluoresc...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Rattus norvegicus)	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of hydrolase activity of full length rat soluble epoxide hydrolase pre-incubated for 30 mins before PHOME substrate addition by fluorescen...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Mus musculus (Mouse))	BDBM50002861 (3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...) Show SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of hydrolase activity of full length mouse soluble epoxide hydrolase pre-incubated for 30 mins before PHOME substrate addition by fluoresc...				J Med Chem 62: 8443-8460 (2019) Article DOI: 10.1021/acs.jmedchem.9b00445 BindingDB Entry DOI: 10.7270/Q2V98CJ7
					More data for this Ligand-Target Pair