Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bile acid receptor (Homo sapiens (Human)) | BDBM50510489 (CHEMBL4462669) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hiroshima International University Curated by ChEMBL | Assay Description Antagonist activity at human FXR expressed in Huh7 cells assessed as inhibition of CDCA-induced FXR response element driven luciferase activity after... | Bioorg Med Chem 27: 2220-2227 (2019) Article DOI: 10.1016/j.bmc.2019.04.029 BindingDB Entry DOI: 10.7270/Q2R49V2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50510489 (CHEMBL4462669) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hiroshima International University Curated by ChEMBL | Assay Description Antagonist activity at GST-tagged FXR LBD (unknown origin) assessed as inhibition of GW4064-induced fluorecein-labeled SRC2-2 coactivator recruitment... | Bioorg Med Chem 27: 2220-2227 (2019) Article DOI: 10.1016/j.bmc.2019.04.029 BindingDB Entry DOI: 10.7270/Q2R49V2G | |||||||||||
More data for this Ligand-Target Pair |