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Found 1 hit Enz. Inhib. hit(s) with Target = 'Biotin carboxylase' and Ligand = 'BDBM50528518'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Biotin carboxylase


(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)		BDBM50528518
PNG
(CHEMBL4551132)
Show SMILES Nc1ncc2cc(c(N)nc2n1)-c1ccccc1-c1cccnc1
Show InChI InChI=1S/C18H14N6/c19-16-15(8-12-10-22-18(20)24-17(12)23-16)14-6-2-1-5-13(14)11-4-3-7-21-9-11/h1-10H,(H4,19,20,22,23,24)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Achaogen Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...

J Med Chem 62: 7489-7505 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00625
BindingDB Entry DOI: 10.7270/Q2JQ14G4
More data for this
Ligand-Target Pair