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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM318856'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM318856
PNG
(6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluoromethy...)
Show SMILES COCCn1nc(C2CC2)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(CF)n2c1
Show InChI InChI=1S/C25H24ClFN6O2/c1-14-11-18(13-31-19(12-27)28-29-24(14)31)33-22(16-5-7-17(26)8-6-16)23-20(25(33)34)21(15-3-4-15)30-32(23)9-10-35-2/h5-8,11,13,15,22H,3-4,9-10,12H2,1-2H3
PDB

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PC cid
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US Patent
n/an/a 25n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...

US Patent US9624247 (2017)


BindingDB Entry DOI: 10.7270/Q28S4S02
More data for this
Ligand-Target Pair