Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM329784'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM329784 (Preparation of 6-(4-chlorophenyl)-8-(3,5-dimethyl-...) Show SMILES Cc1nnc(CC2C=C(c3ccc(Cl)cc3)c3cc(ccc3-n3c(C)nnc23)-c2c(C)noc2C)o1 |t:7| Show InChI InChI=1S/C27H23ClN6O2/c1-14-26(15(2)36-33-14)19-7-10-24-23(11-19)22(18-5-8-21(28)9-6-18)12-20(13-25-31-30-17(4)35-25)27-32-29-16(3)34(24)27/h5-12,20H,13H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For this purpose, a time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used, which measures the binding between N-terminally Hi...				US Patent US9663523 (2017) BindingDB Entry DOI: 10.7270/Q2NC639V
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