Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50265658'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50265658 (CHEMBL4077124) Show SMILES Cn1cc-2c(OCCCCc3cc(Cl)ccc3Oc3ncc(CS(C)(=O)=O)cc-23)cc1=O Show InChI InChI=1S/C23H23ClN2O5S/c1-26-13-19-18-9-15(14-32(2,28)29)12-25-23(18)31-20-7-6-17(24)10-16(20)5-3-4-8-30-21(19)11-22(26)27/h6-7,9-13H,3-5,8,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...				J Med Chem 60: 3828-3850 (2017) Article DOI: 10.1021/acs.jmedchem.7b00017 BindingDB Entry DOI: 10.7270/Q2BR8VPN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50265658 (CHEMBL4077124) Show SMILES Cn1cc-2c(OCCCCc3cc(Cl)ccc3Oc3ncc(CS(C)(=O)=O)cc-23)cc1=O Show InChI InChI=1S/C23H23ClN2O5S/c1-26-13-19-18-9-15(14-32(2,28)29)12-25-23(18)31-20-7-6-17(24)10-16(20)5-3-4-8-30-21(19)11-22(26)27/h6-7,9-13H,3-5,8,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of BRD4 in human NCI-H1299 cells after 24 hrs by Bright-Glo luciferase reporter gene assay				J Med Chem 60: 3828-3850 (2017) Article DOI: 10.1021/acs.jmedchem.7b00017 BindingDB Entry DOI: 10.7270/Q2BR8VPN
					More data for this Ligand-Target Pair