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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50457137'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50457137
PNG
(CHEMBL4217584)
Show SMILES C[C@H]1CN(C(=O)c2ccco2)c2cc(ccc2N1C=O)-c1ccc(cc1)S(C)(=O)=O |r|
Show InChI InChI=1S/C22H20N2O5S/c1-15-13-23(22(26)21-4-3-11-29-21)20-12-17(7-10-19(20)24(15)14-25)16-5-8-18(9-6-16)30(2,27)28/h3-12,14-15H,13H2,1-2H3/t15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



FORMA Therapeutics Inc.

Curated by ChEMBL


Assay Description
Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...

ACS Med Chem Lett 8: 847-852 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00191
BindingDB Entry DOI: 10.7270/Q2WQ06DS
More data for this
Ligand-Target Pair