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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50465547'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50465547
PNG
(CHEMBL4292615)
Show SMILES CCn1cnc2n(Cc3ccc(CNS(=O)(=O)CCc4ccccc4)cc3)c(=O)[nH]c(=O)c12
Show InChI InChI=1S/C23H25N5O4S/c1-2-27-16-24-21-20(27)22(29)26-23(30)28(21)15-19-10-8-18(9-11-19)14-25-33(31,32)13-12-17-6-4-3-5-7-17/h3-11,16,25H,2,12-15H2,1H3,(H,26,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.59E+3n/an/an/an/an/an/a



Aix-Marseille University

Curated by ChEMBL


Assay Description
Inhibition of TEV cleavage site-fused-GST tagged BRD4(BD1) (unknown origin) using SGRGK(Ac)CGK(Ac)-GLGK(Ac)GGAK(Ac)RHRKVG-peptide after 3 hrs by HTRF...

J Med Chem 61: 5719-5732 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00653
BindingDB Entry DOI: 10.7270/Q2Q52S95
More data for this
Ligand-Target Pair