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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50466243'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50466243
PNG
(CHEMBL4286609)
Show SMILES Cc1noc(C)c1-c1ccc2nc(nc(NCc3cccc(Cl)c3)c2c1)-n1cc(CCO)cn1
Show InChI InChI=1S/C25H23ClN6O2/c1-15-23(16(2)34-31-15)19-6-7-22-21(11-19)24(27-12-17-4-3-5-20(26)10-17)30-25(29-22)32-14-18(8-9-33)13-28-32/h3-7,10-11,13-14,33H,8-9,12H2,1-2H3,(H,27,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 140n/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...

Bioorg Med Chem Lett 28: 3483-3488 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.039
BindingDB Entry DOI: 10.7270/Q28S4SKP
More data for this
Ligand-Target Pair