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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50466264'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50466264
PNG
(CHEMBL4282820)
Show SMILES Cc1noc(C)c1-c1ccc2nc(nc(NCc3cccc(Cl)c3)c2c1)-c1cnn(CCC#N)c1
Show InChI InChI=1S/C26H22ClN7O/c1-16-24(17(2)35-33-16)19-7-8-23-22(12-19)26(29-13-18-5-3-6-21(27)11-18)32-25(31-23)20-14-30-34(15-20)10-4-9-28/h3,5-8,11-12,14-15H,4,10,13H2,1-2H3,(H,29,31,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
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GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 120n/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...

Bioorg Med Chem Lett 28: 3483-3488 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.039
BindingDB Entry DOI: 10.7270/Q28S4SKP
More data for this
Ligand-Target Pair