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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50466268'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50466268
PNG
(CHEMBL4287837)
Show SMILES Cc1noc(C)c1-c1ccc2nc(nc(NCc3cccc(Cl)c3)c2c1)C(=O)NCc1cccnc1
Show InChI InChI=1S/C27H23ClN6O2/c1-16-24(17(2)36-34-16)20-8-9-23-22(12-20)25(30-14-18-5-3-7-21(28)11-18)33-26(32-23)27(35)31-15-19-6-4-10-29-13-19/h3-13H,14-15H2,1-2H3,(H,31,35)(H,30,32,33)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 56n/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...

Bioorg Med Chem Lett 28: 3483-3488 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.039
BindingDB Entry DOI: 10.7270/Q28S4SKP
More data for this
Ligand-Target Pair