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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50466275'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50466275
PNG
(CHEMBL4281787)
Show SMILES CN(C)CCN1CCN(CC1)c1nc(NCc2cncc(Cl)c2)c2cc(ccc2n1)-c1c(C)noc1C
Show InChI InChI=1S/C27H33ClN8O/c1-18-25(19(2)37-33-18)21-5-6-24-23(14-21)26(30-16-20-13-22(28)17-29-15-20)32-27(31-24)36-11-9-35(10-12-36)8-7-34(3)4/h5-6,13-15,17H,7-12,16H2,1-4H3,(H,30,31,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 79n/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...

Bioorg Med Chem Lett 28: 3483-3488 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.039
BindingDB Entry DOI: 10.7270/Q28S4SKP
More data for this
Ligand-Target Pair