Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50511851'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50511851 (CHEMBL4590365) Show SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1-n1ccc2ccccc12)S(=O)(=O)CC Show InChI InChI=1S/C27H26N4O4S/c1-4-28-26(32)22-15-20-21(16-30(3)27(33)25(20)29-22)19-14-18(36(34,35)5-2)10-11-24(19)31-13-12-17-8-6-7-9-23(17)31/h6-16,29H,4-5H2,1-3H3,(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6 tagged BRD4 BD2 (352 to 457) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assay				J Med Chem 63: 5585-5623 (2020) Article DOI: 10.1021/acs.jmedchem.0c00628 BindingDB Entry DOI: 10.7270/Q2057K8M
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50511851 (CHEMBL4590365) Show SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1-n1ccc2ccccc12)S(=O)(=O)CC Show InChI InChI=1S/C27H26N4O4S/c1-4-28-26(32)22-15-20-21(16-30(3)27(33)25(20)29-22)19-14-18(36(34,35)5-2)10-11-24(19)31-13-12-17-8-6-7-9-23(17)31/h6-16,29H,4-5H2,1-3H3,(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6 tagged BRD4 BD1 (57 to 168) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assay				J Med Chem 63: 5585-5623 (2020) Article DOI: 10.1021/acs.jmedchem.0c00628 BindingDB Entry DOI: 10.7270/Q2057K8M
					More data for this Ligand-Target Pair