Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50526297'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526297 (CHEMBL4448214) Show SMILES CCOc1cc(ccc1Nc1ncc2N(C)C(=O)[C@@H](CC)N(Cc3cccc(Cl)c3)c2n1)C1CCN(C)CC1 |r| Show InChI InChI=1S/C30H37ClN6O2/c1-5-25-29(38)36(4)26-18-32-30(34-28(26)37(25)19-20-8-7-9-23(31)16-20)33-24-11-10-22(17-27(24)39-6-2)21-12-14-35(3)15-13-21/h7-11,16-18,21,25H,5-6,12-15,19H2,1-4H3,(H,32,33,34)/t25-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Binding affinity to BRD4 (unknown origin) by isothermal calorimetry				J Med Chem 62: 2618-2637 (2019) Article DOI: 10.1021/acs.jmedchem.8b01947 BindingDB Entry DOI: 10.7270/Q28S4TBZ
					More data for this Ligand-Target Pair