Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50559473![]() (CHEMBL4788992) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BRD4-BD1 (unknown origin) by TR-FRET assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116015 BindingDB Entry DOI: 10.7270/Q2TF021T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50559473![]() (CHEMBL4788992) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced TNFalpha secretion preincubated for 1 hr followed by LPS-stimulation and measur... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116015 BindingDB Entry DOI: 10.7270/Q2TF021T | |||||||||||
More data for this Ligand-Target Pair |