Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50578794'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50578794 (CHEMBL4877490) Show SMILES COc1cc2c3n(CC4CCCOC4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C |(5.08,-29.55,;5.08,-31.09,;6.41,-31.86,;7.74,-31.09,;9.08,-31.85,;10.4,-31.08,;10.72,-29.58,;9.68,-28.44,;10.15,-26.97,;9.11,-25.83,;9.59,-24.36,;11.1,-24.04,;12.13,-25.19,;11.66,-26.65,;12.24,-29.41,;13.01,-28.07,;12.87,-30.81,;11.73,-31.84,;11.75,-33.39,;10.41,-34.16,;9.08,-33.39,;7.75,-34.17,;6.41,-33.4,;5.08,-34.17,;3.68,-33.55,;3.36,-32.04,;2.64,-34.69,;3.41,-36.03,;4.92,-35.71,;6.07,-36.74,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in E...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00855 BindingDB Entry DOI: 10.7270/Q23T9N20
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50578794 (CHEMBL4877490) Show SMILES COc1cc2c3n(CC4CCCOC4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C |(5.08,-29.55,;5.08,-31.09,;6.41,-31.86,;7.74,-31.09,;9.08,-31.85,;10.4,-31.08,;10.72,-29.58,;9.68,-28.44,;10.15,-26.97,;9.11,-25.83,;9.59,-24.36,;11.1,-24.04,;12.13,-25.19,;11.66,-26.65,;12.24,-29.41,;13.01,-28.07,;12.87,-30.81,;11.73,-31.84,;11.75,-33.39,;10.41,-34.16,;9.08,-33.39,;7.75,-34.17,;6.41,-33.4,;5.08,-34.17,;3.68,-33.55,;3.36,-32.04,;2.64,-34.69,;3.41,-36.03,;4.92,-35.71,;6.07,-36.74,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced IL-6 secretion incubated for 18 to 24 hrs by MSD assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00855 BindingDB Entry DOI: 10.7270/Q23T9N20
					More data for this Ligand-Target Pair