Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50578796'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50578796 (CHEMBL4869970) Show SMILES COc1cc2c3n(C(C)C4CCOCC4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C |(28.74,-29.9,;28.74,-31.44,;30.07,-32.21,;31.4,-31.44,;32.74,-32.2,;34.07,-31.43,;34.38,-29.93,;33.34,-28.79,;31.84,-29.11,;33.82,-27.32,;35.32,-27,;35.79,-25.54,;34.76,-24.39,;33.25,-24.71,;32.77,-26.18,;35.9,-29.76,;36.67,-28.43,;36.53,-31.16,;35.4,-32.19,;35.41,-33.74,;34.08,-34.51,;32.74,-33.75,;31.41,-34.52,;30.07,-33.75,;28.74,-34.52,;27.34,-33.9,;27.02,-32.39,;26.31,-35.04,;27.07,-36.38,;28.58,-36.06,;29.73,-37.09,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in E...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00855 BindingDB Entry DOI: 10.7270/Q23T9N20
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50578796 (CHEMBL4869970) Show SMILES COc1cc2c3n(C(C)C4CCOCC4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C |(28.74,-29.9,;28.74,-31.44,;30.07,-32.21,;31.4,-31.44,;32.74,-32.2,;34.07,-31.43,;34.38,-29.93,;33.34,-28.79,;31.84,-29.11,;33.82,-27.32,;35.32,-27,;35.79,-25.54,;34.76,-24.39,;33.25,-24.71,;32.77,-26.18,;35.9,-29.76,;36.67,-28.43,;36.53,-31.16,;35.4,-32.19,;35.41,-33.74,;34.08,-34.51,;32.74,-33.75,;31.41,-34.52,;30.07,-33.75,;28.74,-34.52,;27.34,-33.9,;27.02,-32.39,;26.31,-35.04,;27.07,-36.38,;28.58,-36.06,;29.73,-37.09,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced IL-6 secretion incubated for 18 to 24 hrs by MSD assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00855 BindingDB Entry DOI: 10.7270/Q23T9N20
					More data for this Ligand-Target Pair