Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [342-460]/[42-168]' and Ligand = 'BDBM111131'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [342-460]/[42-168] (Homo sapiens (Human))	BDBM111131 (US9695179, 126) Show SMILES CSc1nsc(Sc2c(-c3ccccc3)c3ccc(Cl)cc3[nH]c2=O)n1 Show InChI InChI=1S/C18H12ClN3OS3/c1-24-17-21-18(26-22-17)25-15-14(10-5-3-2-4-6-10)12-8-7-11(19)9-13(12)20-16(15)23/h2-9H,1H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	25
ConverGene LLC US Patent					Assay Description The interactions between test compounds and BRD4 protein containing both bromodomain 1 and bromodomain 2 were measured with human BRD4 protein with N...				US Patent US9695179 (2017) BindingDB Entry DOI: 10.7270/Q21G0JF6
					More data for this Ligand-Target Pair