Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 [368-440] (Homo sapiens (Human)) | BDBM259881 (US10308662, Compound 122 | US9505780, 122) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SignalRx Pharmaceuticals, Inc. US Patent | Assay Description Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma... | US Patent US9505780 (2016) BindingDB Entry DOI: 10.7270/Q22B8WZ1 | |||||||||||
More data for this Ligand-Target Pair |