Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-164]' and Ligand = 'BDBM425402'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425402 (3-[3-chloro-6-(3,5-dimethylisoxazol-4- yl)pyrrolo[...) Show SMILES Cc1noc(C)c1-c1cnc2c(Cl)cn(C(CC#N)C3CC3)c2c1 Show InChI InChI=1S/C18H17ClN4O/c1-10-17(11(2)24-22-10)13-7-16-18(21-8-13)14(19)9-23(16)15(5-6-20)12-3-4-12/h7-9,12,15H,3-5H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair