BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-167]' and Ligand = 'BDBM259880'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-167]


(Homo sapiens (Human))		BDBM259880
PNG
(US10308662, Compound 121 | US9505780, 121)
Show SMILES Fc1ccc(C(=O)Nc2ccc(cc2)-c2csc3c2oc(cc3=O)N2CCOCC2)c(Nc2ccc(I)cc2F)c1F
Show InChI InChI=1S/C30H21F3IN3O4S/c31-21-7-6-19(27(26(21)33)36-23-8-3-17(34)13-22(23)32)30(39)35-18-4-1-16(2-5-18)20-15-42-29-24(38)14-25(41-28(20)29)37-9-11-40-12-10-37/h1-8,13-15,36H,9-12H2,(H,35,39)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 255n/an/an/an/an/an/a



Pfizer



Assay Description
Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...

J Med Chem 50: 2647-54 (2007)


BindingDB Entry DOI: 10.7270/Q24170D7
More data for this
Ligand-Target Pair