Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-167]' and Ligand = 'BDBM259889'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [44-167] (Homo sapiens (Human))	BDBM259889 (US10308662, Compound 130 | US9505780, 130) Show SMILES Cn1ncc2ccc(cc12)-c1csc2c1oc(cc2=O)N1CCOCC1 Show InChI InChI=1S/C19H17N3O3S/c1-21-15-8-12(2-3-13(15)10-20-21)14-11-26-19-16(23)9-17(25-18(14)19)22-4-6-24-7-5-22/h2-3,8-11H,4-7H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...				J Med Chem 50: 2647-54 (2007) BindingDB Entry DOI: 10.7270/Q24170D7
					More data for this Ligand-Target Pair