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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]' and Ligand = 'BDBM215735'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-168]


(Homo sapiens (Human))		BDBM215735
PNG
(US9296748, II-22)
Show SMILES CC(c1ccccn1)n1c(nc2cnc(cc12)N1CCN(C)CC1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C25H29N7O/c1-17-13-19(16-30(4)25(17)33)24-28-21-15-27-23(31-11-9-29(3)10-12-31)14-22(21)32(24)18(2)20-7-5-6-8-26-20/h5-8,13-16,18H,9-12H2,1-4H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 34n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...

US Patent US9296748 (2016)


BindingDB Entry DOI: 10.7270/Q21G0K4K
More data for this
Ligand-Target Pair