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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]' and Ligand = 'BDBM215768'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-168]


(Homo sapiens (Human))		BDBM215768
PNG
(US9296748, III-9)
Show SMILES CC(c1ccccn1)n1c(nc2ccc(OC3CCN(C)CC3)nc12)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C26H30N6O2/c1-17-15-19(16-31(4)26(17)33)24-28-22-8-9-23(34-20-10-13-30(3)14-11-20)29-25(22)32(24)18(2)21-7-5-6-12-27-21/h5-9,12,15-16,18,20H,10-11,13-14H2,1-4H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 217n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...

US Patent US9296748 (2016)


BindingDB Entry DOI: 10.7270/Q21G0K4K
More data for this
Ligand-Target Pair