Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [49-170]' and Ligand = 'BDBM363495'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM363495 (9-(3,5-Dimethylisoxazol-4-yl)-5-methyl-3-phenyl-2,...) Show SMILES Cc1noc(C)c1-c1ccc2c3c1OCC(c1ccccc1)n3n(C)c2=O |(.13,4.58,;1.47,3.81,;1.94,2.35,;3.48,2.35,;3.96,3.81,;5.29,4.58,;2.71,4.72,;2.71,6.26,;4.04,7.03,;4.04,8.57,;2.71,9.34,;1.38,8.57,;1.38,7.03,;.04,6.26,;-1.29,7.03,;-1.29,8.57,;-2.62,9.34,;-2.62,10.88,;-3.96,11.65,;-5.29,10.88,;-5.29,9.34,;-3.96,8.57,;.04,9.34,;.04,10.88,;-1.04,11.97,;2.71,10.88,;3.8,11.97,)| Show InChI InChI=1S/C21H19N3O3/c1-12-18(13(2)27-22-12)15-9-10-16-19-20(15)26-11-17(14-7-5-4-6-8-14)24(19)23(3)21(16)25/h4-10,17H,11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...				US Patent US9850257 (2017) BindingDB Entry DOI: 10.7270/Q2CF9SDT
					More data for this Ligand-Target Pair